Adam supposedly had XY chromosomes, Eve was created from Adam's X chromosomes, so basically Eve was Adam's clone with a duplicated chromosome.
If sin is inherited on the Y chromosome, then all females would still be perfect, because females have XX and thus no "sin chromosomes", that is therefore incorrect.
As far as Jesus is concerned, he'd get the X chromosome from his mother and another Y chromosome would have to be generated from whole cloth. Females can't be cloned into males, whereas male (this has been tested on frogs) could technically be cloned with 2 X chromosomes activated and thus get a female clone.
He would thus carry sin in him at least, even if the genes for 'sin' were magically turned off. So it is entirely possible that had Jesus reproduced (the Mary Magdalene story), his children would either immediately or in a few generations have the sin genes reactivated, because they'd be diluting the activation of those genes.